Overview:Mechanisms of Drug Interactions - Handbook of Experimental Pharmacology 122 - Over the years a number of excellent books have classified and detailed drugdrug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publications have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of "mechanisms" that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drugfood and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be possible for the researcher to develop meaningful animal/biochemical/tissue culture or physicochemical models to which new molecules could be exposed during their development stages. The present position, which largely relies on patients experiencing adverse interactions before they can be established or documented, can hardly be regarded as satisfactory. This present volume is classified into two major parts; firstly, pharmacokinetic drug interactions and, secondly, pharmacodynamic drug interactions.
This book is on page /88f0ff300130a9332bf7ee8997e69000/book/1603729713-9783642646584. It was written by the following authors: James C. McElnay, Peter G. Welling, Patrick F. D'Arcy. Book Mechanisms of Drug Interactions - Handbook of Experimental Pharmacology 122, which can be read online, published by the company: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG. Other books on similar topics can be found in sections: Medicine, Science, Technology. The book was published on 2011-09-28 00:00:00. It has 363 pages and is published in Paperback format and weight 581 g. File for download Mechanisms of Drug Interactions - Handbook of Experimental Pharmacology 122 has PDF format and is called mechanisms-of-drug-interactions-handbook-of-experimental-pharmacology-122.pdf. Other books you can download below. Our nottedeiricercatoriaq.it site is not responsible for the content of PDF files.
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